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Bacillus licheniformis penicillinase has revealed a tetrapeptide se- quence of Leu -Ala-Gly-Cys strain lysogenic for a A vector containing the penicillinase gene
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Some aspects of the induction of penicillinase formation in penicillin-resistant strains of staphylococci have been studied, particularly with respect to methicillin
5-methyltryptophan (5MT) induces penicillinase synthesis in Staphylococcus aureus. The analog is incorporated into protein by both wild-type
Noun, 1. penicillinase-resistant antibiotic - a form of penicillin that is not rendered inactive by penicillinase. Nafcil, nafcillin - a penicillinase-resistant form of
The penicillinase from an Escherichia coli strain harboring an R
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DNA sequence analysis of the structural gene for Bacillus licheniformis penicillinase has revealed a tetrapeptide sequence of Leu-Ala-Gly-Cys within the
A study of the inactivation of penicillinase by Patrick Joseph Campbell; 1 edition; First published in 1958.
the NH2 terminus of themembrane penicillinase because they can be completely blocked the accumulation of penicillinase in the plasma mem- brane, and
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Penicillinase is a specific type of β-lactamase, showing specificity for penicillins, again by hydrolysing the beta-lactam ring. Molecular weights of the various
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Dr. Kim's strategy involves the use of small, specific nucleic acid fragments he has labeled “aptamers” as penicillinase inhibitors so that the
Definition of the term Penicillinase: A beta-lactamase preferentially cleaving penicillins. (Dorland, 28th ed) EC 3.5.2.-.
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CHARLES, BG and RAWAL, BD (1977) ACTION OF CAFFEINE AND THEOPHYLLINE ON STAPHYLOCOCCAL PENICILLINASE SYNTHESIS.
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Rush, Mark G. and Gordon, C. N. and Novick, Richard P. and Warner, Robert C. ( 1969) Penicillinase Plasmid DNA from Staphylococcus aureus
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Penicillinase2 is an enzyme specific for its substrate penicillin. Its inactivating action against penicillin has been utilized for years in the clinical laboratory in
Conditions suitable for induced formation and secretion of penicillinase (EC 3.5. 2.6) in protoplasts of Staphylococcus aureus were determined. No requirement
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The validity of nonsimultaneous association of penicillinase-sensitive β-lactam antibiotics with halogenated isoxazolylpenicillins was tested in
known to be active as a synthetic plant growth hor- mone (2). In two separate series ofexperiments it was found to be effective in reducing the virus con-
Worldwide: Cases of infection caused by penicillinase-producing Neisseria gonorrhoeae (PPNG) have now been detected in 16 different countries - Australia,
This fragment was fused to the distal ends of either the penicillinase (penP) gene By using plasmid pMB9, penicillinase genes (penP and penI) from both the
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PRINCIPLE: Benzylpenicillin + H2O Penicillinase> Benzylpenicilloic Acid. CONDITIONS: T = 25°C, pH = 7.0. METHOD: Titrimetric. REAGENTS:
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Penicillinase production was tested on all samples by iodometric method[10] The penicillinase production was positive in 99 (90%) strains by
5.1.1.2 Penicillinase-resistant penicillins. Most staphylococci are now resistant to benzylpenicillin because they produce penicillinases. Flucloxacillin, however
for the extraction of penicillinase from the cells and culture filtrates of paracolon also reported the preparation of impure penicillinase from unidentified
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(1969) Peyru et al. Journal Of Bacteriology. A series of plasmids harbored by naturally occurring penicillin-resistant strains of Staphylococcus aureus were
Penicillinase-producing strains of S. aureus were isolated from the upper respiratory tract of 28% of a group of children presenting with signs or symptoms of
Rolinson 196I), an enzyme quite distinct from the classic 'penicillinase' which bility that this original 'penicillinase' of Abraham & Chain might have really been
NAD' system were synthesized for a group of staphylococcal penicillinase resistant heterocyclic ring is not enough to confer penicillinase re- sistance, other
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bound penicillinase was localized at or near the cell surface. The P-penicillinase However, the y-penicillinase was tightly bound to the cytoplasmic membrane.
azide on the susceptibility of penicillinase-producing organisms has been studied The latter organism did not gain the ability to produce penicillinase.
The activity of penicillin, alone and in combination with sulbactam, against a heterogeneously methicillin-resistant, penicillinase-producing clinical isolate of
Preventing penicillinase production in antibiotic sensitive Bacillus subtilis. ( Section 1): Factors contributing to penicillin sensitivity and viability of Sarcina lutea in
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Enzyme, Penicillinase (β-lactamase type I). EC, 3.5.2.6. Source, Bacillus cereus 569H. Catalyzed reaction, Hydrolysis of benzylpenicillin. Known substrates
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Catalysis of the reaction: a penicillin + H2O = a substituted beta-amino acid derivative of the penicillin.
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PENICILLINASE hydrolyses the ,&lactam ring in 6-aminopenicillanic acid occurrence of penicillinase producing bacteria has prompted attempts to synthesise
The discovery of penicillinase-resistant penicillins is an impor tant landmark in the antibacterial activity of the five penicillinase-resistant penicillins mentioned
SUMMARY: A penicillinase-positive variant was isolated from a penicillinase- negative strain of Escherichia coli during 'training' towards ampicillin resistance.
In King County, Washington, penicillinase-producing Neisseria gonorrhoeae 268 penicillinase-producing N gonorrhoeae isolates tested, 159 (59%) be-
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A sensitive and reliable potentiometric biosensor for determination of penicillin has been developed by exploiting the self-limiting growth of the
1/20th potency of penicillin GThus, cephalosporins are usually active against penicillinase-producing S. . . penicillinase plasmids and are known as PPNG
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penicillinase ( ) n. Any of various enzymes that are produced by certain bacteria, including most strains of staphylococci, and that hydrolyze and.
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Accession number;00A0101933. Title;Molecular Biological Properties of Penicillinase Within Ampicillin Resistant Pasteurella Piscicida. Author; ISHIDA AKIO
Title: Penicillinase-producing Neisseria Gonorrhoeae Isolates from Different Localities in Southeast Asia: Susceptibility to 15 Antibiotics. Authors: LING Mei Lun
A culture method for the isolation and identification of penicillinase (1- lactamase) -producing Neisseria gonorrhoeae (PPNG) was evaluated in the Philip-
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Penicillinase susceptibility divided the antibiotics into two groups: one Nineteen strains of S. aureus which existed in both a penicillinase producing and a
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The penicillinase from an Escherichia coli strain harboring an R factor RGN823 was purified and its properties were compared with those of a known type I
penicillin, contributed sufficient penicillinase to permit normal rates of acid produc starters; routine treatment of starter milk with penicillinase, but not the manu-
The penicillinase determinants on the 22-MDa plasmid have been found to transpose to the chromosome and from the chromosome to an 18-MDa plasmid
Title: Protein engineering of penicillinase as affinity ligands for bioprocessing. Authors: Imanaka, Tadayuki Kuroda, Akio Wang, Henry Y. Issue Date: 1989
Rabbit antiserum was prepared to the penicillinase of Alcaligenes denitrificans subsp. xylosoxydans GN14062. The antibody gave a single precipitin line in
A strain of Streptococcus faecalis with plasmid-mediated penicillinase production was studied further. Partially purified penicillinase from the S. faecalis strain
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Penicillinase - Where Is The Enzyme Penicillinase Found? : The enzyme penicillinase is a type of beta-lactamase that shows the specifications of penicillin and .
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Determination of MICs using light inocula fails to detect the destructive effect of penicillinase on the antibiotic. This was, however, demonstrated reproducibly by
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Comparison of methods for penicillinase detection in S. aureus. Abstract number: 1733_1134. Kaase M., Lenga S., Szabados F., Sakinc T., Anders A., Friedrich
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Modified ELISA, using penicillinase or urease conjugates, was compared with the For penicillinase, its penicillin substrate was compared for use with three
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penicillinase - Meaning and definition. Look up: penicillinase. penicillinase [n] - enzyme produced by certain bacteria that inactivates penicillin and results in
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5-methyltryptophan (5MT) induces penicillinase synthesis in Since normal penicillinase repressor appears to contain tryptophan even though
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definition of penicillinase - enzyme produced by certain bacteria that inactivates penicillin and results in resistance to that antibiotic.
by the penicillinases of gram-negative bac- teria but may exhibit penicillinase- sensitive drugs has been clearly cases when the penicillinase-resistant peni-
Cephalosporinase and penicillinase activity of Bacillus cereus. Chemical & Substance for Abstract: Cephalosporinase and penicillinase activity of Bacillus
SUMMARY: A method described for the demonstration of penicillinase production For most practical purposes the ability to produce penicillinase can be
The cell-bound and exocellular penicillinases of B. licheniformis 749/C are resistant to trypsin and chymotrypsin. The production of penicillinase sensitive to
Unit of spectinomycin-resistant penicillinase-producing neisseria gonorrhoeae caused bydefinition of penicillin-degrading enzymes that Repress the new
antiserum to staphylococcal penicillinase has the same effect. Concentrated penicillinase from a single strain of staphylococcus was ~ised to prepare a rabbit
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The kinetics of penicillinase induction in Bacillus cereus 569
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A penicillinase plasmid from Staphylococcus aureus and three of its derivatives, all previously identified as extrachromosomal genetic elements, have been
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In eight highly inducible strains of Staphylococcus aureus repression of the formation of penicillinase was temperature-sensitive under conditions suggesting
Summary: The distributions of penicillinase in populations of uninduced, induced and constitutive cultures of Bacillus licheniformis strains 749 and 749/c each
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English > 1 sense of the expression penicillinase-resistant antibiotic: English > penicillinase-resistant antibiotic: 1 sense > noun 1, artifact
Penicillinase is an enzyme produced by certain bacteria which inactivates penicillin by hydrolzing the amide bond in the beta-lactam ring.
Penicillinase (β-lactamase) is a major species of secreted protein produced by Bacillus licheniformis 749. From the pTB2 recombinant plasmid containing the
Dictionary; Thesaurus; Spanish; Medical; Concise Encyclopedia. penicillinase. pen·i·cil·lin·ase. noun \-ˈsi-lə-ˌnās, -ˌnāz\. Definition of PENICILLINASE
Production and purification of the extracellular penicillinase from Bacillus cereus, NRRL The increasing application of penicillinase to testing penicillin sterility
Polyfunctional Penicillinase Plasmid in Staphylococcus epidermidis: The genetic determinant for penicillinase activity was linked with the genetic determinants
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Penicillinase appears to bring about the same transformation, in which a penicillinase to act on penicillin in bicarbonate buffer in the Warburg respirometer
Effect of Cephalosporin C and Various Penicillin Derivatives on. Staphylococcal Penicillinase and Penicillinase-Producing Staphylococci.” (26725). ALBERT G.
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A penicillinase-producing strain oi Neisseria gonorrhoeae was isolated from the of the literature revealed seven cases of DGI due to penicillinase producing
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pen·i·cil·lin·ase (p n -s l -n s ). n. Any of various enzymes that are produced by certain bacteria, including most strains of staphylococci, and that hydrolyze and
Some of the factors influencing synthesis of penicillinase by M. pyogenes are described. Adaptive formation of the enzyme by this organism was not observed
ID, GO:0033250. Name, penicillinase activity. Ontology, Molecular Function. Definition, Catalysis of the reaction: a penicillin + H2O = a substituted beta-amino
penicillinase production were investigated for their susceptibility to methitillin Nineteen strains of S. aureus which existed in both a penicillinase producing and
veillance for cases of infection due to penicillinase-producing Neisseria gonorrhoeae One hundred ninety-one cases of penicillinase-producing gono-
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Microbiology test for rapid detection of beta lactamase production from isolated colonies of Haemophilus influenzae, Neisseria gonorrhoeae, Moraxella
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Optimal Immobilization of Penicillinase for Ion-selective. Electrode. Moon-Hye Hur, Hee-Jin Kang, Hye-Young Min, Ji-Yeun Lee, Ki-Hyun Lee and Moon-Kyu
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Staphylococcal penicillinase was isolated and purified and its activity and properties were compared with Bacillus penicillinase. Relatively little change was
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Transmission of spectinomycin-resistant penicillinase-producing Neisseria gonorrhoeae (PPNG) has been documented for the first time.
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SUMMARY Twelve methods for the demonstration of bacterial penicillinase production by strains After the discovery of penicillinase, one of the fi- lactamase
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Penicillinase, next to catalase, has one of the highest turnover numbers known ( 1.48 Rate of hydrolysis of benzyl penicillin by penicillinase from B. subtilis
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Antistaphylococcal penicillinase sera were prepared using cell-free staphylo- sigl~ihcant difference in the neutralizing ability of anti-B. cereus penicillinase
Importance of penicillinase production for activity of penicillin alone or in combination with sulbactam in experimental endocarditis due to methicillin- resistant
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Penicillinase Listen. noun. Penicillinase n. (Bioch.) An enzyme which destroys the antibacterial activity of penicillin by hydrolyzing the amide bond in the
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The following semisynthetic penicillins, which are resistant to penicillinase,. should be used only The cephaloporins resist the action of penicillinase. They are
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5-Methyl tryptophan was found to be an efficient inducer of penicillinase synthesis in Staphylococcus aureus. Addition of actinomycin D or tryptophan to the
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Emergence of Penicillinase-Producing S. aureus: Recent reports of strains of methicillin-resistant Staphylococcus aureus (MRSA) isolated from children in the
During the first 9 months of 1985, CDC received reports of 6020 cases of penicillinase-producing Neisseria gonorrhoeae (PPNG) among
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Aeromonas sp even though penicillinase Penicillinase-resistantemergence of spectinomycin-resistant penicillinase-producing strain of penicillin by certain
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an Escherichia coli plasmid-coded penicillinase (penicillin amido~ lactamhydrolase, EC 3.5.2.6) are in complete agreement with results derived from the
CBAP is hydrolyzed by the Bacillus penicillinase, but as
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(1977) Günalp, Baykan. Mikrobiyoloji Bulteni. The penicillinase activity and its genetic location in determined by osmotic shock method in the staph. aureus
[1], "Penicillinase from Bacillus licheniformis: nucleotide sequence of the gene and implications for the biosynthesis of a secretory protein in a
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Preparation and Purification of Protein A-Penicillinase Conjugate : penicillinase (specific activity 800 IU/mg) and 0.3 mg protein A were mixed and incubated
Any of various enzymes that are produced by certain bacteria, including most strains of staphylococci, and that hydrolyze and inactivate penicillin. They are used
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The membrane penicillinase ofBacillus licheniformis 7491. C differs from the brane penicillinase to the exo form is probably carried out by a specific
The present paper describes the use of penicillinase, an enzyme specific for the inactivation of penicillin. Patients with penicillin reactions were given
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Title: Sterile Penicillinase from Phage-lysed Staphylococci. Authors: Sabath, Leon D.; Finland, Maxwell. Affiliation: AA(Thorndike Memorial Laboratory, Second
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INFLUENCE. OF PENICILLINASE-PRODUCING. STAPHYLOCOCCI. ON THE ERADICATION. OF GROUP. A STREPTOCOCCI. FROM. THE UPPER
penicillinase denotes p-lactamase preparations that catalyze the hydrolysis of the reactor with penicillinase covalently bonded to derivatized. (sililated) glass
In September 1976 the Center for Disease Control (Atlanta, Georgia) initiated surveillance for cases of infection due to penicillinase-productin
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The effects of subminimal inhibitory concentrations of kanamycin, amikacin and gentamicin on the production of penicillinase by Staphylococcus aureus were
[edit] Noun. penicillinase (countable and uncountable; plural penicillinases). Wikipedia has an article on: Penicillinase · Wikipedia. (biochemistry) A specific type
Hello everybody, Does anyone know how to perform assay for penicillinase?. I ve heard of an assay with nitroefin, but this reagent is very
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Induction of penicillinase (beta-lactamase) in Bacillus licheniformis 749 by 2-(2'- carboxyphenyl)-benzoyl-6-aminopenicillanic acid (CBAP) was
(1972) Sonstein, Baldwin. Journal Of Bacteriology. Read by researchers in: 100 % Environmental Sciences. Two strains of Staphylococcus aureus (PC1 and
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A novel plasmid pXP102-3 which is constructed from Aeromonas sp. No. 212 chromosomal DNA fragment coding for production of xylanase
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Iodometric Assay of Penicillinase. C. J. PERRET. National Institute for Medical Research, London, N.W.7; and Lister Institute of Preventive Medicine, Chelsea
A curve calculated from model B (n = 3) is shown in Fig. 1. This curve fits the ex- perimental points substantially better than those from models A2 and A3 (all
RAPID IDENTIFICATION OF PENICILLINASE-PRODUCING NEISSERIA GONORRHOEAE BY DETECTION OF BETA-LACTAMASE IN URETHRAL EXUDATES.
Penicillinase - definition. Other names beta-Lactamase I; gamma Penicillinase; beta-Lactamase, AER-I; Lactamase RP4, beta; beta Lactamase I; Lactamase III
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The pH optimum for 6-aminopenicillanic acid hydrolysis by both staphylococcal and Bacillus cereus penicillinase is sharper and lower than for benzylpenicillin.
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During routine addition of penicillinase (beta-lactamase) to patients sera, we found that the capacity of some of these sera to kill serum-sensitive gram- negative
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PENICILLINASE-PRODUCING GONOCOCCI IN LIVERPOOL. By - A. Percival, J.E. Corkill, O.P. Arya, J. Rowlands, C.D. Alergant, Elizabeth Rees, E.H. Annels.
Some properties of the induction of penicillinase in Staphylococcus aureus, using benzyl penicillin and cloxacillin as inducers, are described. Optimal conditions
An intensified prevention program has controlled the first outbreak of penicillinase-producing Neisseria gonorrhoeae (PPNG) infections in a
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